genetics

Estimating the Prevalence and Genetic Risk Mechanisms of ARFID in a Large Autism Cohort

This study is the first genetically-informed investigation of avoidant/restrictive food intake disorder (ARFID), an eating disorder that profoundly impacts quality of life for those affected. ARFID is highly comorbid with autism, and we provide the …

VCFdbR: A method for expressing biobank-scale Variant Call Format data in a SQLite database using R

As exome and whole-genome sequencing cohorts grow in size, the data they produce strains the limits of current tools and data structures. The Variant Call Format (VCF) was originally created as part of the 1,000 Genomes project. Flexible and concise …